PAPLN antibody (AA 766-870)

Catalog No. ABIN1724896

This Mouse Monoclonal antibody specifically detects PAPLN in ELISA, WB and ICC. It exhibits reactivity toward Human and Mouse and has been mentioned in 2+ publications.

Quick Overview for PAPLN antibody (AA 766-870) (ABIN1724896)

Target: PAPLN (Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAPLN antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC)

Clone: 5B2E5

Product Details anti-PAPLN Antibody

Binding Specificity: AA 766-870

Purpose: PAPLN Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PAPLN (AA: 766-870) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-PAPLN antibody (ABIN1724896)

Fessler, Kramerova, Kramerov, Chen, Fessler: "Papilin, a novel component of basement membranes, in relation to ADAMTS metalloproteases and ECM development." in: The international journal of biochemistry & cell biology, Vol. 36, Issue 6, pp. 1079-84, (2004) (PubMed).

Kramerova, Kawaguchi, Fessler, Nelson, Chen, Kramerov, Kusche-Gullberg, Kramer, Ackley, Sieron, Prockop, Fessler: "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases." in: Development (Cambridge, England), Vol. 127, Issue 24, pp. 5475-85, (2001) (PubMed).

Target Details for PAPLN

Target: PAPLN (Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN))

Alternative Name: PAPLN

Background: Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases, this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase.

Molecular Weight: 137.7 kDa

Gene ID: 89932

UniProt: O95428