CDX2 antibody (AA 176-303)

Catalog No. ABIN1724921

The Mouse Monoclonal anti-CDX2 antibody has been validated for ELISA and FACS. It is suitable to detect CDX2 in samples from Human. There are 2+ publications available.

Quick Overview for CDX2 antibody (AA 176-303) (ABIN1724921)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 3G9B9

Product Details anti-CDX2 Antibody

Binding Specificity: AA 176-303

Purpose: CDX2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDX2 (AA: 176-303) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CDX2 antibody (ABIN1724921)

Lee, Vogt, Hsiao, Osunkoya: "CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules." in: Tumour biology, Vol. 33, Issue 6, pp. 2185-8, (2012) (PubMed).

Liu, Zhang, Zhan, Brock, Herman, Guo: "CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer." in: Cancer biology & therapy, Vol. 13, Issue 12, pp. 1152-7, (2012) (PubMed).

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background: This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Molecular Weight: 33.5 kDa

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance