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NRF2 antibody (AA 356-589)
NFE2L2
Reactivity: Human
ELISA, IHC
Host: Mouse
Monoclonal
1A6G6
unconjugated
Product Details anti-NRF2 Antibody
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Target
See all NRF2 (NFE2L2) Antibodies
NRF2 (NFE2L2)
(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Binding Specificity
All epitopes for NRF2 antibodies
AA 356-589
Reactivity
All reactivities for NRF2 antibodies
Human
Host
All hosts for NRF2 antibodies
Mouse
Clonality
All clonalities for NRF2 antibodies
Monoclonal
Conjugate
All conjugates for NRF2 antibodies
This NRF2 antibody is un-conjugated
Application
All applications for NRF2 antibodies
ELISA, Immunohistochemistry (IHC)
Purpose
NFE2L2 Antibody
Purification
Purified antibody
Immunogen
Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. Coli.
Clone
1A6G6
Isotype
IgG1
Top Product
Discover our top product NFE2L2 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1/10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
References for anti-NRF2 antibody (ABIN1724931)
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Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal : "NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. " in: Physiological genomics , Vol. 44 , Issue 15 , pp. 754-63 , (2012 ) (PubMed ).
Target Details for NRF2
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Target
NRF2 (NFE2L2)
(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Alternative Name
NFE2L2 (NFE2L2 Products )
Background
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
67.8 kDa
UniProt
Q16236
Pathways
ER-Nucleus Signaling , Negative Regulation of intrinsic apoptotic Signaling
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