Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GABBR2 antibody (AA 319-483)

GABBR2 Reactivity: Human IHC, ELISA, ICC Host: Mouse Monoclonal 5G7F7 unconjugated
Catalog No. ABIN1724937
  • Target See all GABBR2 Antibodies
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Binding Specificity
    • 20
    • 17
    • 14
    • 14
    • 14
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-483
    Reactivity
    • 78
    • 67
    • 53
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 93
    • 24
    Mouse
    Clonality
    • 85
    • 32
    Monoclonal
    Conjugate
    • 32
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABBR2 antibody is un-conjugated
    Application
    • 101
    • 48
    • 48
    • 37
    • 32
    • 21
    • 15
    • 14
    • 13
    • 6
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purpose
    GABBR2 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
    Clone
    5G7F7
    Isotype
    IgG2a
  • Application Notes

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, (2007) (PubMed).

  • Target
    GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
    Alternative Name
    GABBR2 (GABBR2 Products)
    Background
    The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.



    Molecular Weight
    105.8 kDa
    Gene ID
    9568
    UniProt
    O75899
    Pathways
    cAMP Metabolic Process
You are here:
Chat with us!