Aggrecan antibody (C-Term)

Catalog No. ABIN1731431

The Rabbit Polyclonal anti-Aggrecan antibody has been validated for IHC (p). It is suitable to detect Aggrecan in samples from Human.

Quick Overview for Aggrecan antibody (C-Term) (ABIN1731431)

Target: Aggrecan (ACAN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aggrecan antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Aggrecan Antibody

Binding Specificity: C-Term

Specificity: Reacts with human ACAN / Aggrecan

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins, except REG1A (50 % ).

Purification: Antigen affinity purified

Immunogen: Synthetic 16 amino acid peptide from C-terminus of human ACAN / Aggrecan. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Monkey (100%), Marmoset (100%), Rat (100%), Hamster (100%), Mouse (94%), Horse (88%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (10 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.

Target Details for Aggrecan

Target: Aggrecan (ACAN)

Alternative Name: ACAN / Aggrecan

Background: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region

UniProt: P16112

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport