ADAM10 antibody

Catalog No. ABIN1731511

This Rabbit Polyclonal antibody specifically detects ADAM10 in WB, IHC, ELISA, ICC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ADAM10 antibody (ABIN1731511)

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-ADAM10 Antibody

Specificity: Reacts with human ADAM10. Predicted to cross-reacts with bovin, mouse and rat protein.

Purification: Purified

Immunogen: Synthetic peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid.

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
ELISA1:100-1:2000 ICC/IF2 μg/mL IHC-P1:500 WB 1 - 10 μg/mL

Positive control: K562 or Jurkat cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Expiry Date: 6 months

Target Details for ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: ADAM10

Background: ADAM 10 is an endopeptidase involved in cell-cell signaling and many other biological processes

Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10 CDw156 Kuzbanian protein homolog Mammalian disintegrin-metalloprotease CD156c Gene name: : ADAM10, KUZ, MADM

Gene ID: 102

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway