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AIF antibody (C-Term)
AIFM1
Reactivity: Human, Mouse, Rat
WB, ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AIF Antibody
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Target
See all AIF (AIFM1) Antibodies
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Binding Specificity
All epitopes for AIF antibodies
AA 593-606, C-Term
Reactivity
All reactivities for AIF antibodies
Human, Mouse, Rat
Host
All hosts for AIF antibodies
Rabbit
Clonality
All clonalities for AIF antibodies
Polyclonal
Conjugate
All conjugates for AIF antibodies
This AIF antibody is un-conjugated
Application
All applications for AIF antibodies
Western Blotting (WB), Immunocytochemistry (ICC)
Specificity
Reacts with the C-terminus part of human AIF. Cross-reacts with mouse and rat protein.
Purification
Purified
Immunogen
Peptide corresponding to aa 593- 606 at the C-terminus of human AIF. This sequence is identical to those of mouse and rat AIF.
Isotype
IgG
Top Product
Discover our top product AIFM1 Primary Antibody
Alternatives
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1
Reactivity: Human, Mouse, Rat, Pig
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Working dilution: Optimal dilutions should be determined by the end user. The following are guidelines only: ICC5 μg/mL WB0.5 - 2 μg/mL Positive control: K562 cells
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Dilute in PBS or medium which is identical to that used in the assay system.
Storage
-20 °C
Storage Comment
Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
Expiry Date
6 months
Target Details for AIF
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Target
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Alternative Name
Apoptosis-Inducing Factor, AIF (AIFM1 Products )
Synonyms
AIF antibody, CMTX4 antibody, COWCK antibody, COXPD6 antibody, PDCD8 antibody, CG7263 antibody, DmAIF antibody, Dmel\\CG7263 antibody, GB16024 antibody, DDBDRAFT_0187853 antibody, DDBDRAFT_0191137 antibody, DDB_0187853 antibody, DDB_0191137 antibody, aif antibody, pdcd8 antibody, AIFM1 antibody, PCD8 antibody, AIFsh2 antibody, Hq antibody, Pdcd8 antibody, mAIF antibody, Aif antibody, zgc:91994 antibody, apoptosis inducing factor mitochondria associated 1 antibody, allograft inflammatory factor 1 antibody, Apoptosis inducing factor antibody, apoptosis-inducing factor 1, mitochondrial antibody, apoptosis inducing factor antibody, apoptosis inducing factor, mitochondria associated 1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, apoptosis-inducing factor, mitochondrion-associated 1 antibody, AIFM1 antibody, AIF1 antibody, AIF antibody, LOC412212 antibody, aif antibody, aifm1 antibody, Aifm1 antibody
Background
A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is highly conserved between human and mouse and widely expressed in different cell types and tissues. Apoptosis-inducing factor 1, mitochondrial Programmed cell death protein 8 Gene name: AIFM1, AIF, PDCD8
Gene ID
9131
UniProt
O95831
Pathways
Apoptosis , Positive Regulation of Endopeptidase Activity , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Warburg Effect
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