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AIF antibody (C-Term)

AIFM1 Reactivity: Human, Mouse, Rat WB, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1731618
  • Target See all AIF (AIFM1) Antibodies
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Binding Specificity
    • 15
    • 10
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 593-606, C-Term
    Reactivity
    • 105
    • 57
    • 54
    • 22
    • 11
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 93
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 91
    • 14
    Polyclonal
    Conjugate
    • 64
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIF antibody is un-conjugated
    Application
    • 81
    • 35
    • 32
    • 28
    • 21
    • 13
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    Specificity
    Reacts with the C-terminus part of human AIF. Cross-reacts with mouse and rat protein.
    Purification
    Purified
    Immunogen
    Peptide corresponding to aa 593- 606 at the C-terminus of human AIF. This sequence is identical to those of mouse and rat AIF.
    Isotype
    IgG
    Top Product
    Discover our top product AIFM1 Primary Antibody
  • Application Notes
    Working dilution: Optimal dilutions should be determined by the end user.
    The following are guidelines only:
    ICC5 μg/mL WB0.5 - 2 μg/mL

    Positive control: K562 cells
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Dilute in PBS or medium which is identical to that used in the assay system.
    Storage
    -20 °C
    Storage Comment
    Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    Expiry Date
    6 months
  • Target
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Alternative Name
    Apoptosis-Inducing Factor, AIF (AIFM1 Products)
    Background
    A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is highly conserved between human and mouse and widely expressed in different cell types and tissues.

    Apoptosis-inducing factor 1, mitochondrial Programmed cell death protein 8 Gene name: AIFM1, AIF, PDCD8
    Gene ID
    9131
    UniProt
    O95831
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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