AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 593-606)

Details for Product anti-AIFM1 Antibody No. ABIN1731618
Antigen
Epitope
AA 593-606, C-Term
27
17
15
11
10
10
8
7
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
208
106
100
25
15
14
12
10
8
8
6
5
4
2
1
1
Host
Rabbit
192
18
3
2
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
8
5
5
4
4
4
4
4
4
2
2
2
1
1
1
1
1
Application
Immunocytochemistry (ICC), Western Blotting (WB)
177
83
69
43
42
27
15
15
13
9
9
5
3
1
1
Options
Immunogen Peptide corresponding to aa 593- 606 at the C-terminus of human AIF. This sequence is identical to those of mouse and rat AIF.
Isotype IgG
Specificity Reacts with the C-terminus part of human AIF. Cross-reacts with mouse and rat protein.
Purification Purified
Antigen
Alternative Name Apoptosis-Inducing Factor, AIF (AIFM1 Antibody Abstract)
Background A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is highly conserved between human and mouse and widely expressed in different cell types and tissues.

Apoptosis-inducing factor 1, mitochondrial Programmed cell death protein 8 Gene name: AIFM1, AIF, PDCD8
Gene ID 9131
UniProt O95831
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration
Application Notes Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
ICC5 μg/mL WB0.5 - 2 μg/mL

Positive control: K562 cells
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Dilute in PBS or medium which is identical to that used in the assay system.
Storage -20 °C
Storage Comment Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
Expiry Date 6 months