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AIF antibody

AIFM1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC, FACS Host: Mouse Monoclonal 4-00E-07 unconjugated
Catalog No. ABIN968950
  • Target See all AIF (AIFM1) Antibodies
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Reactivity
    • 101
    • 54
    • 52
    • 22
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Monkey
    Host
    • 91
    • 8
    • 2
    • 2
    Mouse
    Clonality
    • 86
    • 16
    Monoclonal
    Conjugate
    • 68
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIF antibody is un-conjugated
    Application
    • 90
    • 38
    • 34
    • 29
    • 26
    • 14
    • 14
    • 13
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human AIF expressed in E. coli.
    Clone
    4-00E-07
    Isotype
    IgG2b
    Top Product
    Discover our top product AIFM1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Son, Jang, Heo, Chung, Choi, Lee: "Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells." in: Apoptosis : an international journal on programmed cell death, Vol. 14, Issue 6, pp. 796-808, (2009) (PubMed).

  • Target
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Alternative Name
    AIF (AIFM1 Products)
    Synonyms
    AIF antibody, CMTX4 antibody, COWCK antibody, COXPD6 antibody, PDCD8 antibody, CG7263 antibody, DmAIF antibody, Dmel\\CG7263 antibody, GB16024 antibody, DDBDRAFT_0187853 antibody, DDBDRAFT_0191137 antibody, DDB_0187853 antibody, DDB_0191137 antibody, aif antibody, pdcd8 antibody, AIFM1 antibody, PCD8 antibody, AIFsh2 antibody, Hq antibody, Pdcd8 antibody, mAIF antibody, Aif antibody, zgc:91994 antibody, apoptosis inducing factor mitochondria associated 1 antibody, allograft inflammatory factor 1 antibody, Apoptosis inducing factor antibody, apoptosis-inducing factor 1, mitochondrial antibody, apoptosis inducing factor antibody, apoptosis inducing factor, mitochondria associated 1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, apoptosis-inducing factor, mitochondrion-associated 1 antibody, AIFM1 antibody, AIF1 antibody, AIF antibody, LOC412212 antibody, aif antibody, aifm1 antibody, Aifm1 antibody
    Background

    Description: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10

    Aliases: AIFM1, AIF, PDCD8, COXPD6, MGC111425

    Molecular Weight
    67 kDa
    Gene ID
    9131
    HGNC
    9131
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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