Axin antibody (C-Term)

Catalog No. ABIN1732155

This anti-Axin antibody is a Rabbit Polyclonal antibody detecting Axin in WB and IHC (p). Suitable for Human.

Quick Overview for Axin antibody (C-Term) (ABIN1732155)

Target: Axin (AXIN1) (Axin 1 (AXIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Axin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Axin Antibody

Binding Specificity: C-Term

Specificity: Reacts with human AXIN1

Purification: Antigen affinity purified

Immunogen: 14 amino acid peptide near the carboxy terminus of human AXIN1

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (5 μg/mL), WB (1 - 2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Target Details for Axin

Target: Axin (AXIN1) (Axin 1 (AXIN1))

Alternative Name: AXIN1

Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.

UniProt: O15169

Pathways: WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling