DC-SIGN/CD209 antibody (Extracellular Domain)

Catalog No. ABIN1733537

The Rabbit Polyclonal anti-DC-SIGN/CD209 antibody has been validated for WB. It is suitable to detect DC-SIGN/CD209 in samples from Human.

Quick Overview for DC-SIGN/CD209 antibody (Extracellular Domain) (ABIN1733537)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DC-SIGN/CD209 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DC-SIGN/CD209 Antibody

Binding Specificity: AA 277-293, Extracellular Domain

Specificity: Reacts with the extracellular domain of human DC-SIGN (ED).

Purification: Purified

Immunogen: Peptide corresponding to aa 277-293 of human DC-SIGN.

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB1 - 2 μg/mL

Positive control: Human placenta tissue lysate

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Expiry Date: 6 months

Target Details for DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Alternative Name: DC-SIGN

Background: DC-SIGN is a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transferred to CD4+ T lymphocytes. Multiple strains of HIV-1, HIV-2, and SIV bind to dendritic cells via DC-SIGN. DC-SIGN is expressed in mucosal tissues, placenta, small intestine, and rectum.

CD209 antigen C-type lectin domain family 4 member L Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1 CD209 Gene name: CD209, CLEC4L

Gene ID: 30835

UniProt: Q9NNX6