MSI1 antibody (AA 5-21)

Catalog No. ABIN1737150

This anti-MSI1 antibody is a Rabbit Polyclonal antibody detecting MSI1 in IHC and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for MSI1 antibody (AA 5-21) (ABIN1737150)

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSI1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MSI1 Antibody

Binding Specificity: AA 5-21

Specificity: Reacts with Musashi1 from human, mouse and rat

Purification: Antigen affinity purified

Immunogen: Reacts with residues 5-21 [APQPGLASPDSPHDPCK] of the human, mouse and rat Musashi 1 protein.

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC-P: 1:10-1:2000 - IHC: 1:10-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for MSI1

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Alternative Name: Musashi1 (Msi1)

Background: Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells.Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia.It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.

Pathways: Stem Cell Maintenance