MYOD1 antibody (N-Term)

Catalog No. ABIN1737175

This Rabbit Polyclonal antibody specifically detects MYOD1 in WB, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for MYOD1 antibody (N-Term) (ABIN1737175)

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-MYOD1 Antibody

Binding Specificity: AA 1-150, N-Term

Specificity: Reacts with human and mouse MyoD

Purification: Antigen affinity purified

Immunogen: A genomic peptide made to an N-terminal region of the human MyoD1 protein (within residues 1-150).

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC(1:100) IF(1:100) WB(1:5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.58 mg/mL

Buffer: PBS, glycerol 50 % , BSA 0.1 %, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Alternative Name: MyoD1

Background: In muscle cell development and differentiation, MYOD1 is a key transcription factor regulating myogenesis. In skeletal muscle, MYOD1 works in tandem with PC4 to promote MEF2C transcription, and thus regeneration of muscle following injury. MYOD1 also influences normal muscle cell formation. Unsurprisingly, MYOD1 is then associated with several diseases of muscle groups, including infantile myofibroma, rhabdomyosarcoma, ulcerative colitis, and sclerosis. MYOD1 is also found in atypical cells of orbital pleomorphic liposarcoma in children.

UniProt: P15172

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development