SNX27 antibody (AA 150-200)

Catalog No. ABIN1739491

This Rabbit Polyclonal antibody specifically detects SNX27 in WB, IHC (p), ICC and IF. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for SNX27 antibody (AA 150-200) (ABIN1739491)

Target: SNX27 (Sorting Nexin 27 (SNX27))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX27 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SNX27 Antibody

Binding Specificity: AA 150-200

Specificity: Reacts with human and mouse ~65 kDa SNX27 protein

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): May cross reacts with rat, bovine and Zebrafish.

Purification: Purified

Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 150-200). [Swiss-Prot# Q96L92]

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/50 to 1/200 - IF : 1/50 to 1/200 - IHC - P : 1/100 - WB : 0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for SNX27

Target: SNX27 (Sorting Nexin 27 (SNX27))

Alternative Name: SNX27

Background: SNX27 is a member of the sorting nexin family of proteins that is involved in endocytic trafficking. In T lymphocytes, SNX27 participates in the endocytic recycling pathway. It has also been shown that the single PDZ domain of SNX27 binds directly to the PDZ binding motif of Kir3 channels, which leads to their downregulation.