Neuroligin 4 antibody (AA 782-945) (APC)

Catalog No. ABIN1741423

This Mouse Monoclonal antibody specifically detects Neuroligin 4 in WB, ICC, IHC and IF. It exhibits reactivity toward Mouse.

Quick Overview for Neuroligin 4 antibody (AA 782-945) (APC) (ABIN1741423)

Target: Neuroligin 4 (NLGN4)

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuroligin 4 antibody is conjugated to APC

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: S98-7

Product Details anti-Neuroligin 4 Antibody (APC)

Binding Specificity: AA 782-945

Specificity: Detects ~125-130 kDa. Does not cross-react with other Neuroligins.

Cross-Reactivity: Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ~45% identity with Neuroligin-1, -2 and -3.

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN1741423 was sufficient for detection of Neuroligin 4 in 20 μg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for Neuroligin 4

Target: Neuroligin 4 (NLGN4)

Alternative Name: Neuroligin 4

Background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Gene ID: 100113365

UniProt: B0F2B4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane