Rab3c antibody

Catalog No. ABIN1742212

This Rabbit Polyclonal antibody specifically detects Rab3c in WB, IP and ICC. It exhibits reactivity toward Human, Mouse, Rat, Cow and Monkey and has been mentioned in 3+ publications.

Quick Overview for Rab3c antibody (ABIN1742212)

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Reactivity: Human, Mouse, Rat, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rab3c antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Rab3c Antibody

Purpose: Rabbit anti-Rab3c antibody

Specificity: Specific for Rab 3c.

Cross-Reactivity (Details): Reacts with: human (Q96E17), rat (P62824), mouse (P62823), monkey, cow. No signal: zebrafish. Other species not tested yet.

Purification: affinity purified

Application Details

Application Notes: WB:1 : 1000 , IP:yes ICC:1 : 500, IHC:not tested yet IHC-P:not tested yet

Comment:

This antibody has been affinity purified with a peptide consisting only of the Rab 3c specific epitope NTRLKETPPPPQPN (aa 211 - 224) of the human protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-Rab3c antibody (ABIN1742212)

Nishioka, Tooi, Isobe, Nakatsuji, Aiba: "BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models." in: Scientific reports, Vol. 6, pp. 33427, (2016) (PubMed).

Pavlos, Grønborg, Riedel, Chua, Boyken, Kloepper, Urlaub, Rizzoli, Jahn: "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13441-53, (2010) (PubMed).

Cai, Reim, Varoqueaux, Tapechum, Hill, Sørensen, Brose, Chow: "Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 49, pp. 19538-43, (2008) (PubMed).

Target Details for Rab3c

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Alternative Name: Rab3c

Background:

Synonyms: Ras-related protein 3C

Antigen Information: Rab3 proteins are the major Rab isoforms in brain and are highly enriched on synaptic vesicles