Syntaxin 1B antibody (AA 171-187)

Catalog No. ABIN1742218

This Rabbit Polyclonal antibody specifically detects Syntaxin 1B in WB, IHC, IP, IHC (p) and ICC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Chicken, Hamster, Pig and Zebrafish (Danio rerio). It has been mentioned in 8+ publications

Quick Overview for Syntaxin 1B antibody (AA 171-187) (ABIN1742218)

Target: Syntaxin 1B (STX1B)

Reactivity: Human, Mouse, Rat, Cow, Chicken, Hamster, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Grade: KO Validated

Product Details anti-Syntaxin 1B Antibody

Binding Specificity: AA 171-187

Purpose: Rabbit anti-Syntaxin1B antiserum

Specificity: Specific for syntaxin 1B

Cross-Reactivity (Details): Reacts with: human (P61266), rat (P61265), mouse (P61264), hamster, cow, pig, chicken, zebrafish. Other species not tested yet.

Purification: antiserum

Immunogen: Synthetic peptide corresponding to AA 171 to 187 from rat Syntaxin1B (UniProt Id: P61265)

Application Details

Application Notes: WB:1 : 1000 , IP:yes ICC:1 : 100 up to 1 : 1000, IHC:1 : 1000, IHC-P:1 : 500,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-Syntaxin 1B antibody (ABIN1742218)

Zhou, Liu, Yu, Han, Fan, Shao, Chen, Qiao, Xie: "Quantitative Proteomic Analysis Reveals Molecular Adaptations in the Hippocampal Synaptic Active Zone of Chronic Mild Stress-Unsusceptible Rats." in: The international journal of neuropsychopharmacology, Vol. 19, Issue 1, (2016) (PubMed).

Arsenault, Ferrari, Niranjan, Cuijpers, Gu, Vallis, OBrien, Davletov: "Stapling of the botulinum type A protease to growth factors and neuropeptides allows selective targeting of neuroendocrine cells." in: Journal of neurochemistry, Vol. 126, Issue 2, pp. 223-33, (2013) (PubMed).

Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

Kabayama, Takeuchi, Taniguchi, Tokushige, Kozaki, Mizutani, Nakamura, Mikoshiba: "Syntaxin 1B suppresses macropinocytosis and semaphorin 3A-induced growth cone collapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 20, pp. 7357-64, (2011) (PubMed).

Tsai, Garcia-Gil, van Haeften, Gadella: "How pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane." in: PLoS ONE, Vol. 5, Issue 6, pp. e11204, (2010) (PubMed).

Sander, Frank, Bolat, Blank, Galli, Bigalke, Bischoff, Lorentz: "Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells." in: European journal of immunology, Vol. 38, Issue 3, pp. 855-63, (2008) (PubMed).

Kubota, Kobayashi, Mori, Higashide, McLaren, Inana: "Changes in retinal synaptic proteins in the transgenic model expressing a mutant HRG4 (UNC119)." in: Investigative ophthalmology & visual science, Vol. 43, Issue 2, pp. 308-13, (2002) (PubMed).

Low, Marmorstein, Miura, Li, Kudo, Marmorstein, Weimbs: "Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype." in: Journal of cell science, Vol. 115, Issue Pt 23, pp. 4545-53, (2002) (PubMed).

Target Details for Syntaxin 1B

Target: Syntaxin 1B (STX1B)

Alternative Name: Syntaxin1B

Background:

Synonyms: p35B, stx1b, stx 1b, SNARES

Antigen Information: K.O. Syntaxin1 is a plasma membrane SNARE protein essential for synaptic vesicle fusion

UniProt: P61265