Syntaxin 7 antibody (AA 1-236)

Catalog No. ABIN1742224

This Rabbit Polyclonal antibody specifically detects Syntaxin 7 in WB, IHC, IP, IHC (p) and ICC. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 12+ publications.

Quick Overview for Syntaxin 7 antibody (AA 1-236) (ABIN1742224)

Target: Syntaxin 7 (STX7)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Grade: KD Validated

Product Details anti-Syntaxin 7 Antibody

Binding Specificity: AA 1-236

Purpose: Rabbit anti-Syntaxin7 antiserum

Specificity: Specific for syntaxin 7.

Cross-Reactivity (Details): Reacts with: human (O15400), rat (O70257), mouse (O70439). Other species not tested yet.

Purification: antiserum

Immunogen: Recombinant protein corresponding to AA 1 to 236 from rat Syntaxin7 (UniProt Id: O70257)

Application Details

Application Notes: WB:1 : 1000 up to 1 : 5000 , IP:yes ICC:1 : 100 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 200,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-Syntaxin 7 antibody (ABIN1742224)

Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

Pattu, Qu, Schwarz, Strauss, Weins, Bhat, Halimani, Marshall, Rettig, Hoth: "SNARE protein expression and localization in human cytotoxic T lymphocytes." in: European journal of immunology, Vol. 42, Issue 2, pp. 470-5, (2012) (PubMed).

Lu, Nozumi, Takeuchi, Abe, Igarashi: "Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells." in: Neuroscience research, Vol. 70, Issue 1, pp. 85-90, (2011) (PubMed).

Flowerdew, Burgoyne: "A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels." in: The Biochemical journal, Vol. 418, Issue 3, pp. 529-40, (2009) (PubMed).

Mannová, Fang, Wang, Deng, McIntosh, Hanash, Beretta: "Modification of host lipid raft proteome upon hepatitis C virus replication." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 12, pp. 2319-25, (2006) (PubMed).

Pisitkun, Bieniek, Tchapyjnikov, Wang, Wu, Shen, Knepper: "High-throughput identification of IMCD proteins using LC-MS/MS." in: Physiological genomics, Vol. 25, Issue 2, pp. 263-76, (2006) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Murray, Wylie, Khromykh, Hume, Stow: "Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha." in: The Journal of biological chemistry, Vol. 280, Issue 11, pp. 10478-83, (2005) (PubMed).

Bared, Buechler, Boettcher, Dayoub, Sigruener, Grandl, Rudolph, Dada, Schmitz: "Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells." in: Molecular biology of the cell, Vol. 15, Issue 12, pp. 5399-407, (2004) (PubMed).

Hasegawa, Zinsser, Rhee, Vik-Mo, Davanger, Hay: "Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 698-720, (2003) (PubMed).

Riedel, Antonin, Fernandez-Chacon, Alvarez de Toledo, Jo, Geppert, Valentijn, Valentijn, Jamieson, Südhof, Jahn: "Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules." in: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6487-97, (2002) (PubMed).

Antonin, Holroyd, Fasshauer, Pabst, Von Mollard, Jahn: "A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function." in: The EMBO journal, Vol. 19, Issue 23, pp. 6453-64, (2000) (PubMed).

Target Details for Syntaxin 7

Target: Syntaxin 7 (STX7)

Alternative Name: Syntaxin7

Background:

Synonyms: SNARES, stx7, stx 7

Antigen Information: K.D. Syntaxin7 is a SNARE protein involved in endosomal and lysosomal fusion reactions

UniProt: O70257

Pathways: Synaptic Vesicle Exocytosis