Syntaxin 11 antibody (AA 1-15)

Catalog No. ABIN1742227

This Rabbit Polyclonal antibody specifically detects Syntaxin 11 in WB, ICC, IP and IHC (p). It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 3+ publications.

Quick Overview for Syntaxin 11 antibody (AA 1-15) (ABIN1742227)

Target: Syntaxin 11 (STX11)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 11 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-Syntaxin 11 Antibody

Binding Specificity: AA 1-15

Purpose: Rabbit anti-Syntaxin11 antibody

Specificity: Specific for syntaxin 11

Cross-Reactivity (Details): Reacts with: rat (A0A0G2K516), mouse (Q9D3G5), human (O75558). Other species not tested yet.

Purification: affinity purified

Immunogen: Synthetic peptide corresponding to AA 1 to 15 from mouse Syntaxin11 (UniProt Id: Q9D3G5)

Application Details

Application Notes: WB:1 : 1000 , IP:yes ICC:1 : 100 up to 1 : 500, IHC:not tested yet IHC-P:1 : 500,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

References for anti-Syntaxin 11 antibody (ABIN1742227)

Koseoglu, Peters, Fitch-Tewfik, Aisiku, Danglot, Galli, Flaumenhaft: "VAMP-7 links granule exocytosis to actin reorganization during platelet activation." in: Blood, Vol. 126, Issue 5, pp. 651-60, (2015) (PubMed).

Golebiewska, Harper, Williams, Savage, Goggs, Fischer von Mollard, Poole: "Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability." in: The Journal of biological chemistry, Vol. 290, Issue 3, pp. 1536-45, (2015) (PubMed).

Ye, Karim, Al Hawas, Pessin, Filipovich, Whiteheart: "Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion." in: Blood, Vol. 120, Issue 12, pp. 2484-92, (2012) (PubMed).

Target Details for Syntaxin 11

Target: Syntaxin 11 (STX11)

Alternative Name: Syntaxin11

Background:

Synonyms: SNARES, stx11, stx 11

Antigen Information: K.O. Syntaxi11 is a SNARE protein abundantly expressed in the immune system

UniProt: Q9D3G5