SV2C antibody (AA 2-16)

Catalog No. ABIN1742260

This Rabbit Polyclonal antibody specifically detects SV2C in WB, IHC and ICC. It exhibits reactivity toward Human, Rat, Mouse, Cow and Dog and has been mentioned in 2+ publications.

Quick Overview for SV2C antibody (AA 2-16) (ABIN1742260)

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Reactivity: Human, Rat, Mouse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SV2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-SV2C Antibody

Binding Specificity: AA 2-16

Specificity: Specific for SV2 C.

Purification: antiserum

Immunogen: Synthetic peptide of rat SV2 C (aa 2-16) coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 500

Comment:

WB: SV2 aggregates after boiling, making it necessary to run SDS-PAGE only with non-boiled samples.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-SV2C antibody (ABIN1742260)

Crèvecœur, Foerch, Doupagne, Thielen, Vandenplas, Moonen, Deprez, Rogister: "Expression of SV2 isoforms during rodent brain development." in: BMC neuroscience, Vol. 14, pp. 87, (2013) (PubMed).

Grønborg, Pavlos, Brunk, Chua, Münster-Wandowski, Riedel, Ahnert-Hilger, Urlaub, Jahn: "Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 1, pp. 2-12, (2010) (PubMed).

Target Details for SV2C

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Alternative Name: SV2 C