Complexin 4 antibody (AA 1-160)

Catalog No. ABIN1742267

The Mouse Monoclonal anti-Complexin 4 antibody has been validated for IHC, WB and IHC (p). It is suitable to detect Complexin 4 in samples from Mouse and Rat. There are 3+ publications available.

Quick Overview for Complexin 4 antibody (AA 1-160) (ABIN1742267)

Target: Complexin 4 (CPLX4)

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Complexin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Clone: 171H8

Product Details anti-Complexin 4 Antibody

Binding Specificity: AA 1-160

Purpose: Mouse anti-Complexin4 IgG

Specificity: Specific for complexin 4

Cross-Reactivity (Details): Reacts with: rat (D3ZM85), mouse (Q80WM3). Other species not tested yet.

Purification: purified IgG

Immunogen: Recombinant protein corresponding to AA 1 to 160 from mouse Complexin4 (UniProt Id: Q80WM3)

Isotype: IgG1

Application Details

Application Notes: WB:1 : 1000 , IP:not tested yet ICC:not tested yet IHC:1 : 1000 up to 1 : 2000, IHC-P:1 : 200,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References for anti-Complexin 4 antibody (ABIN1742267)

Vaithianathan, Henry, Akmentin, Matthews: "Functional roles of complexin in neurotransmitter release at ribbon synapses of mouse retinal bipolar neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 9, pp. 4065-70, (2015) (PubMed).

Landgraf, Mühlhans, Dedek, Reim, Brandstätter, Ammermüller: "The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina." in: The European journal of neuroscience, Vol. 36, Issue 4, pp. 2470-81, (2012) (PubMed).

Xue, Stradomska, Chen, Brose, Zhang, Rosenmund, Reim: "Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 22, pp. 7875-80, (2008) (PubMed).

Target Details for Complexin 4

Target: Complexin 4 (CPLX4)

Alternative Name: Complexin4

Background:

Synonyms: CPX 4, SNARE associated, CPX4, CPX IV, CPXIV, eye-retina

Antigen Information: K.O. Complexin4 is a nerve-terminal syntaxin binding protein in retinal ribbon synapses

UniProt: Q80WM3