DLG2 antibody (AA 22-37)

Catalog No. ABIN1742273

The Rabbit Polyclonal anti-DLG2 antibody has been validated for WB, IP and ICC. It is suitable to detect DLG2 in samples from Human, Rat, Mouse and Hamster. There are 5+ publications available.

Quick Overview for DLG2 antibody (AA 22-37) (ABIN1742273)

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Reactivity: Human, Rat, Mouse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-DLG2 Antibody

Binding Specificity: AA 22-37

Specificity: Specific for PSD 93.

Purification: antiserum

Immunogen: Synthetic peptide DGPHDHSLPRLTHEVR (aa 22-37 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: not recommended
IHC: not tested yet

Comment:

ICC: The affinity purified antibody is recommended.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-DLG2 antibody (ABIN1742273)

Requena, Parra, Baust, Quiroz, Leak, Garcia-Olivares, Torres: "The molecular chaperone Hsc70 interacts with the vesicular monoamine transporter-2." in: Journal of neurochemistry, Vol. 110, Issue 2, pp. 581-94, (2009) (PubMed).

Smalla, Sahin, Putzke, Tischmeyer, Gundelfinger, Kreutz: "Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis." in: Neurochemical research, Vol. 34, Issue 8, pp. 1405-9, (2009) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Morciano, Burré, Corvey, Karas, Zimmermann, Volknandt: "Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis." in: Journal of neurochemistry, Vol. 95, Issue 6, pp. 1732-45, (2005) (PubMed).

Valtschanoff, Burette, Davare, Leonard, Hell, Weinberg: "SAP97 concentrates at the postsynaptic density in cerebral cortex." in: The European journal of neuroscience, Vol. 12, Issue 10, pp. 3605-14, (2000) (PubMed).

Target Details for DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Alternative Name: PSD 93

Background: Synonyms: Chapsin 110, DLG 2