Neuroligin 3 antibody (AA 710-824)

Catalog No. ABIN1742288

The Rabbit Polyclonal anti-Neuroligin 3 antibody has been validated for WB. It is suitable to detect Neuroligin 3 in samples from Rat and Mouse. There are 2+ publications available.

Quick Overview for Neuroligin 3 antibody (AA 710-824) (ABIN1742288)

Target: Neuroligin 3 (NLGN3)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroligin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KO Validated

Product Details anti-Neuroligin 3 Antibody

Binding Specificity: AA 710-824

Purpose: Rabbit anti-Neuroligin3 antibody

Specificity: Specific for neuroligin 3. No signal on neuroligin 3 knockouts. Detects other neuroligins when heavily overexpressed.

Cross-Reactivity (Details): Reacts with: rat (Q62889), mouse (Q8BYM5). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 710 to 824 from mouse Neuroligin3 (UniProt Id: Q8BYM5)

Application Details

Application Notes: WB:1 : 1000 , IP:not tested yet ICC:not recommended IHC:not recommended IHC-P:not recommended ELISA:

Comment:

ELISA: Suitable as detector antibody for sandwich-ELISA with ABIN1742285 as capture antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

References for anti-Neuroligin 3 antibody (ABIN1742288)

Runkel, Rohlmann, Reissner, Brand, Missler: "Promoter-like sequences regulating transcriptional activity in neurexin and neuroligin genes." in: Journal of neurochemistry, Vol. 127, Issue 1, pp. 36-47, (2013) (PubMed).

Suckow, Comoletti, Waldrop, Mosedale, Egodage, Taylor, Chessler: "Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion." in: Endocrinology, Vol. 149, Issue 12, pp. 6006-17, (2008) (PubMed).

Target Details for Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Alternative Name: Neuroligin3

Background:

Synonyms: Synaptic Adhesion Proteins, Neuroligin 3, Neuroligin3, Nlgn3

Antigen Information: K.O. Neuroligins are postsynaptic cell adhesion molecules

UniProt: Q8BYM5

Pathways: Synaptic Membrane