SDCBP antibody (AA 1-298)

Catalog No. ABIN1742301

This anti-SDCBP antibody is a Rabbit Polyclonal antibody detecting SDCBP in WB, IP and IHC (p). Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 4+ publications.

Quick Overview for SDCBP antibody (AA 1-298) (ABIN1742301)

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDCBP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KD Validated

Product Details anti-SDCBP Antibody

Binding Specificity: AA 1-298

Purpose: Rabbit anti-Syntenin antibody

Specificity: Detects human protein with higher sensitivity. Recognizes syntenin 1 and 2.

Cross-Reactivity (Details): Reacts with: human (O00560, Q9H190). Weaker signal: rat (Q9JI92, Q4KLN0), mouse (O08992, Q99JZ0). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 1 to 298 from human Syntenin1 (UniProt Id: O00560)

Application Details

Application Notes: WB:1 : 100 up to 1 : 1000 , IP:yes ICC:not tested yet IHC:not tested yet IHC-P:1 : 1000,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

References for anti-SDCBP antibody (ABIN1742301)

Binamé, Sakry, Dimou, Jolivel, Trotter: "NG2 regulates directional migration of oligodendrocyte precursor cells via Rho GTPases and polarity complex proteins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 26, pp. 10858-74, (2013) (PubMed).

Sala-Valdés, Gordón-Alonso, Tejera, Ibáñez, Cabrero, Ursa, Mittelbrunn, Lozano, Sánchez-Madrid, Yáñez-Mó: "Association of syntenin-1 with M-RIP polarizes Rac-1 activation during chemotaxis and immune interactions." in: Journal of cell science, Vol. 125, Issue Pt 5, pp. 1235-46, (2012) (PubMed).

Sulka, Lortat-Jacob, Terreux, Letourneur, Rousselle: "Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10659-71, (2009) (PubMed).

Meerschaert, Remue, De Ganck, Staes, Boucherie, Gevaert, Vandekerckhove, Kleiman, Gettemans: "The tandem PDZ protein Syntenin interacts with the aminoacyl tRNA synthetase complex in a lysyl-tRNA synthetase-dependent manner." in: Journal of proteome research, Vol. 7, Issue 11, pp. 4962-73, (2008) (PubMed).

Target Details for SDCBP

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Alternative Name: Syntenin

Background:

Synonyms: SDCB1, Pbp1

Antigen Information: K.D. Syntenin is an ubiquitously expressed PDZ domain protein

UniProt: O00560