RIMS2 antibody (AA 925-1114)

Catalog No. ABIN1742309

The Rabbit Polyclonal anti-RIMS2 antibody has been validated for WB, IHC and IP. It is suitable to detect RIMS2 in samples from Rat and Mouse. There is 1 publication available.

Quick Overview for RIMS2 antibody (AA 925-1114) (ABIN1742309)

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-RIMS2 Antibody

Binding Specificity: AA 925-1114

Specificity: Specific for RIM 2

Cross-Reactivity (Details): no cross reactivity to RIM 1.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant protein (aa 925-1114) of rat RIM 2, a stretch of divergent aa connecting the Rab binding motif and the PDZ domain.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: not tested yet
IHC: 1 : 1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-RIMS2 antibody (ABIN1742309)

Regus-Leidig, Specht, Tom Dieck, Brandstätter: "Stability of active zone components at the photoreceptor ribbon complex." in: Molecular vision, Vol. 16, pp. 2690-700, (2010) (PubMed).

Target Details for RIMS2

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Alternative Name: RIM 2

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis