Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RIMS2 antibody (Center)

RIMS2 Reactivity: Human, Rat, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500608
  • Target See all RIMS2 Antibodies
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    Binding Specificity
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 27
    • 14
    • 4
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 22
    • 10
    • 1
    Rabbit
    Clonality
    • 25
    • 8
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIMS2 antibody is un-conjugated
    Application
    • 15
    • 10
    • 9
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Rim2. Rim2 is known to exist in multiple isoforms, this antibody should recognize most of them. It is predicted to have no cross-reactivity to other Rim proteins.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    Rim2 antibody was raised against a 17 amino acid peptide near the center of the human Rim2.
    Isotype
    IgG
    Top Product
    Discover our top product RIMS2 Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
    Alternative Name
    RIMS2 (RIMS2 Products)
    Synonyms
    OBOE antibody, RAB3IP3 antibody, RIM2 antibody, 2810036I15Rik antibody, AW048769 antibody, Rab3ip2 antibody, Rim2(+40A) antibody, Rim2(+44A) antibody, Rim2(+4A) antibody, Serg2 antibody, Syt3-rs antibody, mKIAA0751 antibody, Nim2 antibody, Rim2 antibody, RIMS2 antibody, MGC159469 antibody, rims2 antibody, zgc:73064 antibody, drs antibody, drsp antibody, mema antibody, np-a antibody, pinin antibody, pnn antibody, pnn-a antibody, pnn-b antibody, sdk3 antibody, regulating synaptic membrane exocytosis 2 antibody, regulating synaptic membrane exocytosis 2a antibody, pinin, desmosome associated protein S homeolog antibody, RIMS2 antibody, Rims2 antibody, rims2a antibody, pnn.S antibody
    Background
    Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.Synonyms: KIAA0751, RAB3IP3, RIM 2, RIM2, Rab-3-interacting molecule 2, Rab-3-interacting protein 3, Regulating synaptic membrane exocytosis protein 2
    Gene ID
    9699
    NCBI Accession
    NP_001093587
    UniProt
    Q9UQ26
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
You are here:
Support