SH3G2 antibody (AA 256-276)

Catalog No. ABIN1742336

The Rabbit Polyclonal anti-SH3G2 antibody has been validated for WB, IHC, IHC (p), ICC and IP. It is suitable to detect SH3G2 in samples from Mouse and Rat. There are 2+ publications available.

Quick Overview for SH3G2 antibody (AA 256-276) (ABIN1742336)

Target: SH3G2 (Endophilin-A1 (SH3G2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3G2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Grade: KO Validated

Product Details anti-SH3G2 Antibody

Binding Specificity: AA 256-276

Purpose: Rabbit anti-Endophilin1 antiserum

Specificity: Specific for endophilin 1.

Cross-Reactivity (Details): Reacts with: rat (O35179), mouse (Q62420). Other species not tested yet.

Purification: antiserum

Immunogen: Synthetic peptide corresponding to AA 256 to 276 from mouse Endophilin1 (UniProt Id: Q62420)

Application Details

Application Notes: WB:1 : 1000 up to 1 : 10000 , IP:yes ICC:1 : 500, IHC:1 : 200, IHC-P:1 : 1000,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-SH3G2 antibody (ABIN1742336)

Fuchs, Brandstätter, Regus-Leidig: "Evidence for a Clathrin-independent mode of endocytosis at a continuously active sensory synapse." in: Frontiers in cellular neuroscience, Vol. 8, pp. 60, (2014) (PubMed).

Wahl, Katiyar, Schmitz: "A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 25, pp. 10278-300, (2013) (PubMed).

Target Details for SH3G2

Target: SH3G2 (Endophilin-A1 (SH3G2))

Alternative Name: Endophilin1

Background:

Synonyms: SH3P4, SH3GL2, Endophilin A1

Antigen Information: K.O. Endophilin1 is an SH3 domain protein involved in clathrin mediated endocytosis

UniProt: Q62420

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation