Homer 1b/c (C-Term) antibody

Catalog No. ABIN1742339

The Rabbit Polyclonal anti- antibody has been validated for WB, ICC, IHC and IP. It is suitable to detect in samples from Human, Mouse and Rat. There are 3+ publications available.

Quick Overview for Homer 1b/c (C-Term) antibody (ABIN1742339)

Target: Homer 1b/c

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details

Binding Specificity: C-Term

Purpose: Rabbit anti-Homer1b/c antibody

Specificity: Specific for homer 1b and 1c

Cross-Reactivity (Details): Reacts with: human (Q86YM7-1), rat (Q9Z214-2, Q9Z214-1), mouse. Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to the c-terminal half of human Homer 1b (UniProt Id: Q86YM7-1)

Application Details

Application Notes: WB:1 : 1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References

Yoon, Piguel, Khalatyan, Dionisio, Savas, Penzes: "Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome." in: Molecular psychiatry, (2021) (PubMed).

Kim, Kong, Yamamoto, Kuramoto, Huang, Wang, Hong, Xiao, Levine, Qiu, Zhao, Miller, Dong, Meltzer, Xu, He: "An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system." in: Science advances, Vol. 7, Issue 8, (2021) (PubMed).

Tao-Cheng, Thein, Yang, Reese, Gallant: "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation." in: Neuroscience, Vol. 266, pp. 80-90, (2014) (PubMed).

Target Details

Target: Homer 1b/c

Alternative Name: Homer1b/c

Background:

Synonyms: VesL 1, Syn47, Homer1 b, Homer1 c, Homer1 bc

Antigen Information: Homer1 , 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors

UniProt: Q86YM7