Caveolin-1 antibody (AA 1-17)

Catalog No. ABIN1742344

This Rabbit Polyclonal antibody specifically detects Caveolin-1 in WB, IHC, IP and ICC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Pig, Cow and Monkeyand has been mentioned in 1 publication.

Quick Overview for Caveolin-1 antibody (AA 1-17) (ABIN1742344)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Caveolin-1 Antibody

Binding Specificity: AA 1-17

Specificity: Specific for cavaeolin 1.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide MSGGKYVDSEGHLYTVP (aa 1-17) coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue.

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 100 up to 1 : 500

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-Caveolin-1 antibody (ABIN1742344)

Ferru-Clément, Fresquet, Norez, Métayé, Becq, Kitzis, Thoreau: "Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118943, (2015) (PubMed).

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: Caveolin 1

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals