LIPA3 antibody (AA 463-604)

Catalog No. ABIN1742356

This Rabbit Polyclonal antibody specifically detects LIPA3 in WB and ICC. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 4+ publications.

Quick Overview for LIPA3 antibody (AA 463-604) (ABIN1742356)

Target: LIPA3 (PPFIA3) (Liprin alpha 3 (PPFIA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIPA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-LIPA3 Antibody

Binding Specificity: AA 463-604

Specificity: Specific for liprin-alpha 3

Cross-Reactivity (Details): no cross reaction to isoforms 1, 2, 4.

Purification: antiserum

Immunogen: Recombinant protein of mouse liprin-alpha 3 (aa 463-604).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 500
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-LIPA3 antibody (ABIN1742356)

Lenihan, Saha, Heimer-McGinn, Cryan, Feng, Young: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." in: Molecular neurobiology, (2016) (PubMed).

Girach, Craig, Rocca, Henley: "RIM1α SUMOylation is required for fast synaptic vesicle exocytosis." in: Cell reports, Vol. 5, Issue 5, pp. 1294-301, (2013) (PubMed).

Sakamoto, Ishizaki, Okawa, Watanabe, Arakawa, Watanabe, Narumiya: "Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization." in: Journal of cell science, Vol. 125, Issue Pt 1, pp. 108-20, (2012) (PubMed).

Lazarevic, Schöne, Heine, Gundelfinger, Fejtova: "Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10189-200, (2011) (PubMed).

Target Details for LIPA3

Target: LIPA3 (PPFIA3) (Liprin alpha 3 (PPFIA3))

Alternative Name: Liprin-Alpha3

Background: Synonyms: Syd 2