LIPA3 antibody (AA 463-604)

Catalog No. ABIN1742356

This Rabbit Polyclonal antibody specifically detects LIPA3 in WB and ICC. It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 4+ publications.

Quick Overview for LIPA3 antibody (AA 463-604) (ABIN1742356)

Target: LIPA3 (PPFIA3) (Liprin alpha 3 (PPFIA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIPA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-LIPA3 Antibody

Binding Specificity: AA 463-604

Purpose: Rabbit anti-Liprin-alpha3 antiserum

Specificity: Specific for liprin-alpha 3

Cross-Reactivity (Details): Reacts with: human (O75145), rat (Q91Z79), mouse (P60469). No signal: zebrafish. Other species not tested yet.

Purification: antiserum

Immunogen: Recombinant protein corresponding to AA 463 to 604 from mouse Liprin-alpha3 (UniProt Id: P60469)

Application Details

Application Notes: WB:1 : 1000 , IP:not tested yet ICC:1 : 500, IHC:not tested yet IHC-P:not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-LIPA3 antibody (ABIN1742356)

Lenihan, Saha, Heimer-McGinn, Cryan, Feng, Young: "Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice." in: Molecular neurobiology, (2016) (PubMed).

Girach, Craig, Rocca, Henley: "RIM1α SUMOylation is required for fast synaptic vesicle exocytosis." in: Cell reports, Vol. 5, Issue 5, pp. 1294-301, (2013) (PubMed).

Sakamoto, Ishizaki, Okawa, Watanabe, Arakawa, Watanabe, Narumiya: "Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization." in: Journal of cell science, Vol. 125, Issue Pt 1, pp. 108-20, (2012) (PubMed).

Lazarevic, Schöne, Heine, Gundelfinger, Fejtova: "Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10189-200, (2011) (PubMed).

Target Details for LIPA3

Target: LIPA3 (PPFIA3) (Liprin alpha 3 (PPFIA3))

Alternative Name: Liprin-alpha3

Background:

Synonyms: Syd 2, Syd2, Ppfia3

Antigen Information: Liprin-alpha3 is involved in the development of presynaptic active zones

UniProt: P60469