Neurexin 1 antibody (AA 1328-1421)

Catalog No. ABIN1742366

The Rabbit Polyclonal anti-Neurexin 1 antibody has been validated for WB. It is suitable to detect Neurexin 1 in samples from Rat and Mouse. There are 2+ publications available.

Quick Overview for Neurexin 1 antibody (AA 1328-1421) (ABIN1742366)

Target: Neurexin 1 (NRXN1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurexin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KO Validated

Product Details anti-Neurexin 1 Antibody

Binding Specificity: AA 1328-1421

Purpose: Rabbit anti-Neurexin1 antibody

Specificity: Specific for neurexin 1. The epitope is present in alpha- and beta-neurexin 1.

Cross-Reactivity: Mouse

Cross-Reactivity (Details): Reacts with: rat (Q63372), mouse (Q9CS84). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 1328 to 1421 from rat Neurexin1 (UniProt Id: Q63372)

Application Details

Application Notes: WB:1 : 500 up to 1 : 1000 , ICC:not recommended IHC:not recommended IHC-P:not tested yet

Comment:

WB: Unboiled samples yield stronger signals.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-Neurexin 1 antibody (ABIN1742366)

Bot, Schweizer, Ben Halima, Fraering: "Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases." in: The Journal of biological chemistry, Vol. 286, Issue 4, pp. 2762-73, (2011) (PubMed).

Lim, Kwon, Lee, Moon, Jeong, Park, Kim, Park, Lee, Ryu, Yu, Chung, Kim, Myung, Lee: "Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn." in: The EMBO journal, Vol. 28, Issue 22, pp. 3564-78, (2009) (PubMed).

Target Details for Neurexin 1

Target: Neurexin 1 (NRXN1)

Alternative Name: Neurexin1

Background:

Synonyms: Neurexin1, Neurexin 1, Synaptic Adhesion Proteins

Antigen Information: K.O. Neurexins are receptor-like neuronal cell-surface protein

UniProt: Q63372

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development