LRRC7 antibody (AA 877-891)

Catalog No. ABIN1742390

The Rabbit Polyclonal anti-LRRC7 antibody has been validated for ICC. It is suitable to detect LRRC7 in samples from Mouse and Rat. There is 1 publication available.

Quick Overview for LRRC7 antibody (AA 877-891) (ABIN1742390)

Target: LRRC7 (Leucine Rich Repeat Containing 7 (LRRC7))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC7 antibody is un-conjugated

Application: Immunocytochemistry (ICC)

Product Details anti-LRRC7 Antibody

Binding Specificity: AA 877-891

Specificity: Specific for densin 180.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Synthetic peptide of rat densin (aa 877-891) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.

Application Details

Application Notes: WB: not recommended
IP: not tested yet
ICC: 1 : 500
IHC: not tested yet

Comment:

The crude antiserum is recommended for WB (stronger signals).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-LRRC7 antibody (ABIN1742390)

Wheeler, Groth, Ma, Barrett, Owen, Safa, Tsien: "Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression." in: Cell, Vol. 149, Issue 5, pp. 1112-24, (2012) (PubMed).

Target Details for LRRC7

Target: LRRC7 (Leucine Rich Repeat Containing 7 (LRRC7))

Alternative Name: Densin 180

Pathways: Synaptic Membrane