Neurobeachin antibody (AA 952-1320)

Catalog No. ABIN1742399

The Rabbit Polyclonal anti-Neurobeachin antibody has been validated for WB, IHC and ICC. It is suitable to detect Neurobeachin in samples from Mouse and Rat. There are 4+ publications available.

Quick Overview for Neurobeachin antibody (AA 952-1320) (ABIN1742399)

Target: Neurobeachin (NBEA)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurobeachin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-Neurobeachin Antibody

Binding Specificity: AA 952-1320

Specificity: Specific for neurobeachin.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant mouse neurobeachin (aa 952-1320).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: 1 : 1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-Neurobeachin antibody (ABIN1742399)

Farzana, Zalm, Chen, Li, Grant, Smit, Toonen, Verhage: "Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways." in: Molecular neurobiology, (2015) (PubMed).

Nair, Lauks, Jung, Cooke, de Wit, Brose, Kilimann, Verhage, Rhee: "Neurobeachin regulates neurotransmitter receptor trafficking to synapses." in: The Journal of cell biology, Vol. 200, Issue 1, pp. 61-80, (2013) (PubMed).

Lauks, Klemmer, Farzana, Karupothula, Zalm, Cooke, Li, Smit, Toonen, Verhage: "Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin." in: PLoS ONE, Vol. 7, Issue 6, pp. e39420, (2012) (PubMed).

Niesmann, Breuer, Brockhaus, Born, Wolff, Reissner, Kilimann, Rohlmann, Missler: "Dendritic spine formation and synaptic function require neurobeachin." in: Nature communications, Vol. 2, pp. 557, (2011) (PubMed).

Target Details for Neurobeachin

Target: Neurobeachin (NBEA)

Alternative Name: Neurobeachin

Background: Synonyms: NBEA