Abeta 38/40/42 (AA 1-16) antibody (Biotin)

Catalog No. ABIN1742438

The Mouse Monoclonal anti-Abeta 38/40/42 antibody is suitable to detect Abeta 38/40/42 in samples from Human and Mouse. It has been validated for IHC and IHC (p).

Quick Overview for Abeta 38/40/42 (AA 1-16) antibody (Biotin) (ABIN1742438)

Target: Abeta 38/40/42

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: NT78

Product Details

Binding Specificity: AA 1-16

Purpose: Mouse anti-Abeta38/40/42/43 IgG

Specificity: Specific for Abeta 38, 40, 42.

Cross-Reactivity (Details): Reacts with: human (P05067), mouse (P12023). Other species not tested yet.

Characteristics: labeled with Biotin. Biotin is a small vitamin B complex molecule. Its small size minimizes interference with antibody binding sites and allows for efficient conjugation without compromising antibody functionality. Biotin conjugated antibodies can be easily detected with Avidin/Streptavidin based secondary detection systems. The streptavidin-biotin bond is one of the strongest non-covalent biological bonds known.

Purification: purified IgG

Immunogen: Synthetic peptide corresponding to AA 1 to 16 from human Abeta (UniProt Id: P05067) Epitop AA 4 to 16 from human Abeta (UniProt Id: P05067)

Isotype: IgG2b

Application Details

Application Notes: WB:not tested yet IP:not tested yet ICC:not tested yet IHC:1 : 200 up to 1 : 500, IHC-P:1 : 200 up to 1 : 500,

Comment:

ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS

Preservative: Without preservative

Handling Advice: Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

Target Details

Target: Abeta 38/40/42

Background:

Synonyms: Beta-APP, ABPP, Abeta, Abeta 38, Abeta 40, Abeta 42, Abeta 43

Antigen Information: Abeta peptides are major components of neuritic plaques in Alzheimer's disease

UniProt: P05067