SYCN antibody (AA 22-134)

Catalog No. ABIN1742468

The Mouse Monoclonal anti-SYCN antibody has been validated for WB. It is suitable to detect SYCN in samples from Mouse and Rat. There are 4+ publications available.

Quick Overview for SYCN antibody (AA 22-134) (ABIN1742468)

Target: SYCN (Syncollin (SYCN))

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SYCN antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 87-1

Product Details anti-SYCN Antibody

Binding Specificity: AA 22-134

Purpose: Mouse anti-Syncollin IgG

Specificity: Specific for syncollin.

Cross-Reactivity (Details): Reacts with: rat (O35775), mouse (Q8VCK7). Other species not tested yet.

Purification: purified IgG

Immunogen: Recombinant protein corresponding to AA 22 to 134 from rat Syncollin (UniProt Id: O35775)

Isotype: IgG1

Application Details

Application Notes: WB:1 : 1000 up to 1 : 5000 , IP:not tested yet ICC:not tested yet IHC:not tested yet IHC-P:not recommended

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References for anti-SYCN antibody (ABIN1742468)

Bach, Borta, Ackermann, Faust, Borchers, Schrader: "The secretory granule protein syncollin localizes to HL-60 cells and neutrophils." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 8, pp. 877-88, (2006) (PubMed).

Antonin, Wagner, Riedel, Brose, Jahn: "Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion." in: Molecular and cellular biology, Vol. 22, Issue 5, pp. 1545-54, (2002) (PubMed).

Kalus, Hodel, Koch, Kleene, Edwardson, Schrader: "Interaction of syncollin with GP-2, the major membrane protein of pancreatic zymogen granules, and association with lipid microdomains." in: The Biochemical journal, Vol. 362, Issue Pt 2, pp. 433-42, (2002) (PubMed).

An, Hansen, Hodel, Jahn, Edwardson: "Analysis of the association of syncollin with the membrane of the pancreatic zymogen granule." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11306-11, (2000) (PubMed).

Target Details for SYCN

Target: SYCN (Syncollin (SYCN))

Alternative Name: Syncollin

Background:

Synonyms: SNARE associated, Sync

Antigen Information: Syncollin is a zymogen granules protein

UniProt: O35775