GluN 2B (AA 42-60) antibody

Catalog No. ABIN1742497

This Rabbit Polyclonal antibody specifically detects GluN 2B in WB and IP. It exhibits reactivity toward Rat and Mouse. It has been mentioned in 2+ publications

Quick Overview for GluN 2B (AA 42-60) antibody (ABIN1742497)

Target: GluN 2B

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details

Binding Specificity: AA 42-60

Purpose: Rabbit anti-GluN2B antibody

Specificity: Specific for GluN 2B

Cross-Reactivity (Details): Reacts with: rat (Q00960), mouse (Q01097). Other species not tested yet.

Purification: affinity purified

Immunogen: Synthetic peptide corresponding to AA 42 to 60 from rat GluN2B (UniProt Id: Q00960)

Application Details

Application Notes: WB:1 : 1000 ICC:not tested yet IHC:not tested yet IHC-P:not tested yet

Comment:

IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References

Szutorisz, DiNieri, Sweet, Egervari, Michaelides, Carter, Ren, Miller, Blitzer, Hurd: "Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 39, Issue 6, pp. 1315-23, (2014) (PubMed).

Gut, Beske, Hubbard, Lyman, Hamilton, McNutt: "Novel application of stem cell-derived neurons to evaluate the time- and dose-dependent progression of excitotoxic injury." in: PLoS ONE, Vol. 8, Issue 5, pp. e64423, (2013) (PubMed).

Target Details

Target: GluN 2B

Alternative Name: GluN2B

Background:

Synonyms: NMDA-receptor 2 B, GluN2B, GluN 2B, glutamate receptor, NR2B, GRIN2B

Antigen Information: GluN2A and B are subunits of ionotropic NMDA type glutamate receptors

UniProt: Q00960