CLCN3 antibody (AA 558-689)

Catalog No. ABIN1742509

This Rabbit Polyclonal antibody specifically detects CLCN3 in WB. It exhibits reactivity toward Rat and Mouseand has been mentioned in 1 publication.

Quick Overview for CLCN3 antibody (AA 558-689) (ABIN1742509)

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLCN3 Antibody

Binding Specificity: AA 558-689

Specificity: Epitope present in both splice variants of ClC 3.

Cross-Reactivity (Details): May cross react to ClC 4 and 5, due to sequence homology.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant protein (aa 558-689 of mouse ClC 3)

Application Details

Application Notes: WB: 1 : 1000
IP: not tested yet
ICC: not tested yet
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-CLCN3 antibody (ABIN1742509)

Eckenstaler, Lessmann, Brigadski: "CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons." in: Journal of cell science, Vol. 129, Issue 7, pp. 1378-90, (2016) (PubMed).

Target Details for CLCN3

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Alternative Name: Chloride Channel 3

Background: Synonyms: ClC 3, ClCN 3