CHGB antibody (AA 407-677)

Catalog No. ABIN1742518

This Rabbit Polyclonal antibody specifically detects CHGB in WB, IHC, ICC and IHC (p). It exhibits reactivity toward Mouse and Rat and has been mentioned in 3+ publications.

Quick Overview for CHGB antibody (AA 407-677) (ABIN1742518)

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHGB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-CHGB Antibody

Binding Specificity: AA 407-677

Purpose: Rabbit anti-Chromogranin B antibody

Specificity: Specific chromogranin B.

Cross-Reactivity (Details): Reacts with: rat (O35314), mouse (P16014). Other species not tested yet.

Purification: affinity purified

Immunogen: Recombinant protein corresponding to AA 407 to 677 from mouse Chromogranin B (UniProt Id: P16014)

Application Details

Application Notes: WB:1 : 1000 , IP:not tested yet ICC:1 : 500, IHC:1 : 500, IHC-P:1 : 500 up to 1 : 10000,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-CHGB antibody (ABIN1742518)

Alvarez-Saavedra, De Repentigny, Yang, OMeara, Yan, Hashem, Racacho, Ioshikhes, Bulman, Parks, Kothary, Picketts: "Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice." in: Cell reports, Vol. 17, Issue 3, pp. 862-875, (2016) (PubMed).

Farina, van de Bospoort, He, Persoon, van Weering, Broeke, Verhage, Toonen: "CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons." in: eLife, Vol. 4, (2015) (PubMed).

Walter, Kurps, de Wit, Schöning, Toft-Bertelsen, Lauks, Ziomkiewicz, Weiss, Schulz, Fischer von Mollard, Verhage, Sørensen: "The SNARE protein vti1a functions in dense-core vesicle biogenesis." in: The EMBO journal, Vol. 33, Issue 15, pp. 1681-97, (2014) (PubMed).

Target Details for CHGB

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Alternative Name: Chromogranin B

Background:

Synonyms: CgB, Secretogranin, Secretogranin-1, ChgB

Antigen Information: K.O. Chromogranin B is expressed at high levels in the neuroendocrine system

UniProt: P16014