This Mouse Monoclonal antibody specifically detects Anthrax Protective Antigen in EIA, IF and IHC (p). It exhibits reactivity toward Bacillus anthracis.
PA
Reactivity: Bacillus anthracis
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA (1/20-1/200). Immunofluorescence (1/10-1/50). Immunohistochemistry on Paraffin Sections (1/10-1/50). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.1 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
Anthrax Protective Antigen (PA)
Alternative Name
Bacillus Anthracis Protective Antigen
Background
B. anthracis is an obligate parasite, from the Bacillus genus, and causes anthrax, an acute infectious disease which mainly affects ruminants. Anthrax can also infect humans, and is known to infect in three forms, cutaneous, inhalation and gastrointestinal. Inhalation and gastrointestinal infection is highly lethal if not treated quickly. B. anthracis primarily infects macrophages, causing immune suppression and resulting in a massive terminal bacteraemia.Synonyms: Anthrax toxins translocating protein, PA-83, PA83, pagA