Cortisol antibody
Quick Overview for Cortisol antibody (ABIN180821)
Target
See all Cortisol AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: Hydrocortisone
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Purification
- Purified
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Immunogen
- Synthetic Corticosterone conjugated to Bovine Serum Albumin.
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Isotype
- IgG3
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Application Notes
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ELISA: 1/500-1/5000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Cortisol
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Target Type
- Hormone
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Background
- Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.Synonyms: Hydrocortisone
Target
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