IL-3 antibody

Catalog No. ABIN181037

The Rat Monoclonal anti-IL-3 antibody has been validated for EIA. It is suitable to detect IL-3 in samples from Human.

Quick Overview for IL-3 antibody (ABIN181037)

Target: IL-3 (Interleukin 3 (IL-3))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-3 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: BVD3-1F9

Product Details anti-IL-3 Antibody

Specificity: This antibody recognises interleukin 3.

Characteristics: Synonyms: IL-3, Multipotential colony-stimulating factor, Hematopoietic growth factor,P-cell-stimulating factor, MCGF, Mast cell growth factor

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Borate buffered saline

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for IL-3

Target: IL-3 (Interleukin 3 (IL-3))

Alternative Name: Interleukin-3 / IL3

Background: The pleiotropic IL3 (Interleukin 3) is a 15 kDa cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL3 acts in hematopoiesis by controlling the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and the monocytes/macrophages. It induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes and is expressed by activated T cells, mast cells, and natural killer cells. IL3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL3 has also been shown to protect mast cells from undergoing apoptosis.Synonyms: Hematopoietic growth factor, IL-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor

Gene ID: 3562

UniProt: P08700

Pathways: JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy