COL6 antibody
Quick Overview for COL6 antibody (ABIN181166)
Target
See all COL6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
 - This antibody reacts to Collagen VI.
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Purification
 - Purified
 
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Application Notes
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                        ELISA. Immunoblotting. Immunofluorescence. Immunohistochemistry on frozen sections. 
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 
                                            
Restrictions
 - For Research Use only
 
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Concentration
 - 0.4 mg/mL
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Buffer
 - Borate buffered saline
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Handling Advice
 - Avoid repeated freezing and thawing.
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Storage
 - -20 °C
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Storage Comment
 - The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only.
 
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- COL6 (Collagen, Type VI (COL6))
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Background
 - Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL6A1
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Gene ID
 - 1291
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NCBI Accession
 - NP_001839
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UniProt
 - P12109
 
Target
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