COL6 antibody

Catalog No. ABIN135056

There are 2+ publications for this product available. The Goat Polyclonal anti-COL6 antibody is suitable to detect COL6 in samples from Human, Mouse, Rat, Cow, Pig, Rabbit, Cynomolgus and Dog. It has been validated for WB, ELISA, ICC, IHC (p), IHC (fro) and IEM.

Quick Overview for COL6 antibody (ABIN135056)

Target: COL6 (Collagen, Type VI (COL6))

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Cynomolgus, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This COL6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Product Details anti-COL6 Antibody

Purpose: Goat Anti-Type VI Collagen-UNLB

Specificity: Reacts with conformational determinants on type VI collagen Referenced species reactivities include - Human 1-3,5,6,9-11,13,14,16-19 Canine 20 Mouse 12,15 Cynomolgus 20 Rat 8,20 Porcine 4 Bovine 17 Rabbit 7

Cross-Reactivity (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Characteristics: Purified Anti-Type VI Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, and western blotting assays.

Purification: Purified by affinity chromatography on type VI collagen covalently linked to agarose, cross-adsorbed against Collagen types I, II, III, IV, and V for minimal reactivity

Immunogen: Type VI collagen

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Pooled antisera from goats hyperimmunized with type VI collagen

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Borate buffered saline, pH 8.2

Storage: 4 °C

Storage Comment: 2-8°C

References for anti-COL6 antibody (ABIN135056)

Olona, Terra, Ko, Grau-Bové, Pinent, Ardevol, Diaz, Moreno-Moral, Edin, Bishop-Bailey, Zeldin, Aitman, Petretto, Blay, Behmoaras: "Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis." in: Molecular metabolism, Vol. 11, pp. 18-32, (2019) (PubMed).

Dias, Kim, Holl, Werne Solnestam, Lundeberg, Carlén, Göritz, Frisén: "Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury." in: Cell, Vol. 173, Issue 1, pp. 153-165.e22, (2019) (PubMed).

Target Details for COL6

Target: COL6 (Collagen, Type VI (COL6))

Alternative Name: TypeVI Collagen

Background:

Description: Goat Anti-Type VI Collagen-UNLB

NCBI_Official_Symbol: COL6A1, COL6A2, COL6A3

Synoynms: COL6

Gene ID: 1291, 1292

UniProt: P12109