CD28 antibody (PE)

Catalog No. ABIN1819166

Product Details anti-CD28 Antibody (PE)

Target: CD28

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD28 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Recognizes the bovine homologue of human CD28, a co-stimulatory cell surface molecule expressed by T cell subsets. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). Clone CC219 has been shown to be able to stimulate bovine T lymphocytes in combination with anti-bovine CD3. For functional studies it is recommended to use the low endotoxin and preservative free format of this,. Clone CC219 has previously been published under the alternative clone designation F848EC4.

Purification: Protein G purified

Immunogen: Plasmid DNA encoding the bovine CD28 gene.

Type of Immunogen: Genetic immunization

Clone: CC219

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Protect from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD28

Target: CD28

Alternative Name: CD28 (CD28 Products)

Background: Name/Gene ID: CD28

Synonyms: CD28, CD28 antigen, CD28 antigen (Tp44), Tp44, CD28 Molecule

Gene ID: 940

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response