CCR8 antibody (AA 7-33)

Catalog No. ABIN1819307

The Goat Polyclonal anti-CCR8 antibody has been validated for WB, ELISA, IHC and IHC (p). It is suitable to detect CCR8 in samples from Mouse.

Quick Overview for CCR8 antibody (AA 7-33) (ABIN1819307)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCR8 Antibody

Binding Specificity: AA 7-33

Specificity: Recognizes mouse CDw198, otherwise known as CCR8 (C-C chemokine receptor type 8), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts a high-affinity receptor for the chemokine I-309 (CCL1), implicated in the regulation of monocyte chemotaxis and thymocyte apoptosis. CDw198 is constitutively expressed by monocytes, preferentially expressed on Th2 (type 2 helper T) cells, and acts as a co-receptor with CD4 for HIV1 infection.

Purification: Affinity purified

Immunogen: Synthetic peptide PNVTMTDYYPDFFTAPCDAEFLLRGSM corresponding to amino acids 7-33 of mouse CDw198. Percent identity by BLAST analysis: Mouse (100%), Rat (81%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:100000), IHC, IHC-P (1:400), WB (1:1000)

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 0.1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background: Name/Gene ID: CCR8
Subfamily: Chemokine
Family: GPCR

Synonyms: CCR8, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, CC-CKR-8, Chemokine (C-C) receptor 8, CDw198 antigen, CKRL1, CMKBR8, Chemokine receptor-like 1, CMKBRL2, CKR-L1, GPRCY6, TER1, C-C CKR-8, CC chemokine receptor 8, CC-chemokine receptor chemr1, CCR-8, CDw198, CY6, GPR-CY6

Gene ID: 1237

UniProt: P51685