CD8 antibody (PE)

Catalog No. ABIN1819615

This Rat Monoclonal antibody specifically detects CD8 in FACS, IF, IHC (fro) and IHC. It exhibits reactivity toward Dog.

Quick Overview for CD8 antibody (PE) (ABIN1819615)

Target: CD8

Reactivity: Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)

Clone: YCATE55-9

Product Details anti-CD8 Antibody (PE)

Specificity: Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.

Purification: Protein G purified

Immunogen: Canine CD8 alpha chimeric human IgG1 Fc fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1), IF, IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Protect from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD8

Target: CD8

Alternative Name: CD8