CD52 antibody (PE)

Catalog No. ABIN1819674

Product Details anti-CD52 Antibody (PE)

Target: CD52

Reactivity: Human, Monkey, Rhesus Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This CD52 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox)

Specificity: Reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kD, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanized versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies ,.

Purification: Protein A purified

Immunogen: Human lymphocytes.

Type of Immunogen: Cells

Clone: YTH34-5

Isotype: IgG2b

Application Details

Application Notes: Approved: Ctox, Flo (1:1), IHC, IHC-Fr, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Protect from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD52

Target: CD52

Alternative Name: CD52 (CD52 Products)

Background: Name/Gene ID: CD52

Synonyms: CD52, Cambridge pathology 1 antigen, CD52 antigen, CD52 Molecule, CDW52, CAMPATH-1 antigen, He5

Gene ID: 1043