LAMP2 antibody (FITC)

Catalog No. ABIN1819854

This anti-LAMP2 antibody is a Mouse Monoclonal antibody detecting LAMP2 in WB, FACS, IP and IF. Suitable for Human, Dog and Mink.

Quick Overview for LAMP2 antibody (FITC) (ABIN1819854)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivity: Human, Dog, Mink

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP2 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AC17

Product Details anti-LAMP2 Antibody (FITC)

Specificity: Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.

No Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Protein G purified

Immunogen: MDCK (Madin-Darby Canine Kidney) cells.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1), IF, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Protect from light.

Storage: 4 °C,-20 °C

Storage Comment: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Target Details for LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Alternative Name: LAMP2 / CD107b

Background: Name/Gene ID: LAMP2
Family: Cancer

Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2

Gene ID: 3920

Pathways: Autophagy