CD8 antibody

Catalog No. ABIN1834900

Product Details anti-CD8 Antibody

Target: CD8

Reactivity: Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (IHC)

Specificity: Was clustered as Canine CD8 in the First Canine Leukocyte Antigen Workshop. YCATE55.9 reacts with a rat cell line transfected with cDNA for canine CD8alpha and blocks MHC class I dependant T-cell responses in vitro and in vivo. Has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma.

Purification: Protein G purified

Immunogen: Canine CD8a chimeric human IgG1 Fc fusion protein.

Type of Immunogen: Fusion protein

Clone: YCATE55-9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Dog

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD8

Target: CD8

Alternative Name: CD8 (CD8 Products)