CD37 antibody
Quick Overview for CD37 antibody (ABIN1837524)
Target
See all CD37 (TSPAN26) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- The antigen CD37 defined by IPO-24 is B lineage restricted and is strongly expressed throughout B cell ontogeny from pre-B cells until the plasmoblasts. CD37 is an extensively glycosylated molecule and usually two and sometimes three N-linked carbohydrate chain are attached to the protein. IPO24 reacts with human B cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are not labeled. IPO-24 stains B cell follicles and the most strongly labeled elements are mantle zone lymphoid cells. Neutrophils, macrophages, thymocytes and dendritic reticulum cells are negative.
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Purification
- Purified
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Immunogen
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IPO-24 was generated after immunization of BALB/c mice with spleen cells of a patient with hairy cell leukemia. Mice splenocytes were fused with the P3-X63-Ag8.653 mouse myeloma cell line.
Type of Immunogen: Cells -
Isotype
- IgG2b
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C.
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- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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Alternative Name
- CD37
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Background
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Name/Gene ID: CD37
Family: Tetraspan
Synonyms: CD37, CD37 antigen, CD37 Molecule, Leukocyte surface antigen CD37, gp52-40, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26, Tspan-26 -
Gene ID
- 951
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UniProt
- P11049
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Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Target
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