MVP antibody
Quick Overview for MVP antibody (ABIN1838176)
Target
See all MVP AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Clone 1011 is specific for a 104-kD protein. This mAb is one of four mAb which recognize different epitopes of the protein. This 104-kD protein is the major vault protein and has shown to interact with the estrogen receptor The protein is part of a very large vault ribonucleoprotein complex present in all eukaryotic cells and its structure and protein composition is highly conserved. Because of the size, shape, and protein and RNA composition of this complex the particles are different from other ribonucleoproteins. Source: A BALB/c mouse was immunized with 5 gg of affinity purified nuclear extract proteins. Spleen cells were fused with equal number of Sp0Ag-14 myeloma cells. Cells whose supernatant showed a positive signal for a 104-kD band were selected and cloned by limited dilution.
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Purification
- Purified
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Immunogen
- 5 ug of affinity purified nuclear extract proteins. Spleen cells were fused with equal number of Sp0Ag-14 myeloma cells. Cells whose supernatant showed a positive signal for a 104-kD band were selected and cloned by limited dilution.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C.
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- MVP (Major Vault Protein (MVP))
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Alternative Name
- MVP / LRP
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Background
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Name/Gene ID: MVP
Synonyms: MVP, Major vault protein, VAULT1, LRP -
Gene ID
- 9961
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UniProt
- Q14764
Target
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